BMS-433771

目录号: GC68779纯度: >99.00%
BMS-433771 是一种有效的呼吸道合胞病毒 (RSV) 抑制剂,具有口服活性。BMS-433771 对 A 组和 B 组 RSV 均有效, EC50 均值为 20 nM。BMS-433771 可用于呼吸道疾病的研究。

BMS-433771
Cas No.: 543700-68-1
规格价格库存数量操作
10mg¥6,930.00现货
1
25mg¥9,900.00现货
1

文献被引

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产品描述 Description

BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of Had proplactic efficacy via oral dosing in both animal models.
Showed RSV infection more sensitive to inhibition in the BALB/c mouse host than in the cotton rat.

[1]. Christopher Cianci, et al. Antiviral activity and molecular mechanism of an orally active respiratory syncytial virus fusion inhibitor. J Antimicrob Chemother
[2]. Christopher Cianci, et al. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Antimicrob Agents Chemother. 2004 Jul;48(7):2448-54.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
543700-68-1
分子式
C21H23N5O2
分子量
377.44 g/mol
溶解性
DMSO : 6.25 mg/mL (16.56 mM; ultrasonic and warming and heat to 60°C); H<sub>2</sub>O : 2.5 mg/mL (6.62 mM; ultrasonic and adjust pH to 4 with HCl)
保存条件
Store at -20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol