BM-131246 is an oral antidiabetic agent.
BM-131246 is absorbed quickly and attains approximately proportional increase of the plasma levels in ob/ob mice. After repeated oral doses the terminal half-lives is about 4 h for BM-131246[1].
[1]. Heitzmann T, et al. Dose proportionality studies of novel thiazolidinedione derivatives as potent antidiabetic agents in mice. Arzneimittelforschung. 1995 Dec;45(12):1284-8.