Blumeatin is a flavonoid that has been found in Blumea and has antioxidant and anticancer activities.1,2,3 It scavenges DPPH radicals in a cell-free assay with a 50% scavenging capacity (SC50) value of 90.8 ?g/ml.1 Blumeatin (10 and 100 ?M) decreases carbon tetrachloride-induced lipid peroxidation in isolated rhesus monkey hepatocytes.2 It is also cytotoxic to KB oral carcinoma cells (IC50 = 47.72 ?g/ml).3
1.Nessa, F., Ismail, Z., Mohamed, N., et al.Free radical-scavenging activity of organic extracts and of pure flavonoids of Blumea balsamifera DC leavesFood Chem.88(2)243-252(2004) 2.Zhao, J.H., Xu, S.-B., Wang, Z.-L., et al.Protective actions of blumea flavanones on primary cultured hepatocytes and liver subcellular organelle against lipid peroxidationJ. Chin. Pharma. Sci.7(3)152-156(1998) 3.Saewan, N., Koysomboon, S., and Chantrapromma, K.Anti-tyrosinase and anti-cancer activities of flavonoids from Blumea balsamifera DCJ. Med. Plant Res.5(6)1018-1025(2011)