Bactenecin is a cyclic cationic peptide with antimicrobial activity.1 It is found in bovine neutrophils. Bactenecin is active against the bacteria E. coli and S. aureus (IC50s = 8 and 32 mg/ml, respectively) and the fungus C. albicans (MIC = 64 mg/ml).2
1.Romeo, D., Skerlavaj, B., Bolognesi, M., et al.Structure and bactericidal activity of an antibiotic dodecapeptide purified from bovine neutrophilsJ. Biol. Chem.263(20)9573-9575(1988) 2.Hancock, R.E.W.Cationic peptides: Effectors in innate immunity and novel antimicrobialsLancet Infect.Dis.1(3)156-164(2001)
















