β-Interleukin II (44-56)

目录号: GP10080纯度: >98%同义词: H2N-Ile-Leu-Asn-Gly-Ile-Asn-Asn-Tyr-Lys-Asn-Pro-Lys-Leu-OH

Cytokine,regulating WBC


β-Interleukin II (44-56)
Cas No.: 309247-07-2
规格价格库存数量操作
5mg¥441.00现货
1
10mg¥756.00现货
1
25mg¥1,008.00现货
1

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产品描述 Description

β-Interleukin II (44-56), (C68H113N19O19) is a peptide with the sequence NH2-ILE-LEU-ASN-GLY-ILE-ASN-ASN-TYR-LYS-ASN-PRO-LYS-LEU-COOH, MW= 1500.7. Interleukin 2 (IL-2) belongs to the interleukin family, a type of cytokine signaling molecule in the immune system, and it is a protein that regulates the activities of the white blood cells (leukocytes, often lymphocytes) responsible for immunity. IL-2, a soluble hormone-like mediator of the immune system, was the first interleukin molecule to be identified and characterized. It is necessary for the growth, proliferation, and differentiation of T cells to become 'effector' T cells. IL-2 is normally produced by T cells during an immune response and is necessary for the development of T cell immunologic memory, which depends upon the expansion of the number and function of antigen-selected T cell clones.IL-2 is also necessary for the maturation of a subset of T cells, termed regulatory T cells, during T cell development in the thymus.

References:
1. Cantrell DA, Smith KA (June 1984). "The interleukin-2 T-cell system: a new cell growth model". Science 224 (4655): 1312–6.
2. Smith KA (May 1988). "Interleukin-2: inception, impact, and implications". Science 240 (4856): 1169–76.
3. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (August 1995). "Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases". J. Immunol. 155 (3): 1151–64.
4. ThorntonAM, Shevach EM (July 1998). "CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production". J. Exp. Med. 188 (2): 287–96.

产品文档 Product Documents

化学性质Chemical Properties

CAS 号
309247-07-2
同义词
H2N-Ile-Leu-Asn-Gly-Ile-Asn-Asn-Tyr-Lys-Asn-Pro-Lys-Leu-OH
SMILES
C[C@@H](CC)[C@H](N)C(N[C@H](CC(C)C)C(N[C@H](CC(N)=O)C(NCC(N[C@H]([C@@H](CC)C)C(N[C@H](CC(N)=O)C(N[C@H](CC(N)=O)C(N[C@H](CC1=CC=C(O)C=C1)C(N[C@H](CCCCN)C(N[C@H](CC(N)=O)C(N2CCC[C@H]2C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
分子式
C68H113N19O19
分子量
1500.74 g/mol
溶解性
≥ 150mg/mL in DMSO
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol