Azide-polysarcosine50 is an azide-containing form of the amine-functionalized hydrophilic polymer polysarcosine50.1 Azide-polysarcosines have been used in the formation of hydrophobicity-masking antibody-drug conjugates for the selective release of monomethyl auristatin E to tumors in rats.
References:
[1]. Viricel, W., Fournet, G., Beaumel, S., et al.Monodisperse polysarcosine-based highly-loaded antibody-drug conjugatesChem. Sci.10(14)4048-4053(2019).
















