Atractylodinol, an antimicrobial, is aPRRSV (porcine reproductive and respiratory syndrome virus)inhibitor. Atractylodinol inhibitsTGF-β receptorI recycling by binding to vimentin (KDof 454 nM) and inducing the formation of filamentous aggregates.
References:
[1].Mengjiao Hao, et al. Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin. Mol Ther. 2023 Oct 4;31(10):3015-3033.
[2].Alyssa B Evans, et al. Identification and characterization of small molecule inhibitors of porcine reproductive and respiratory syndrome virus. Antiviral Res. 2017 Oct:146:28-35.
















