APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases.
APC 366 (TFA) (5 mg/kg/0.1 ml; s.c.) reduces the eosinophil recruitment induced by PAR-2 activating peptide[1].
References:
[1]. Matos NA, et al. Mast cell tryptase induces eosinophil recruitment in the pleural cavity of mice via proteinase-activated receptor 2. Inflammation. 2013;36(6):1260-1267.
















