Antimycin A complex is a bacterial metabolite complex that has been found in Streptomyces and is composed of the major components antimycin A1 , -A2 , -A3 , and -A4 , as well as minor components, including antimycin A5 and -A6, among others.1 It induces the synthesis of carotenoids in M. marinum when used at concentrations ranging from 3.3 to 160 µM.2 Antimycin A complex (25-125 ppb) has teleocidal activity against goldfish.1
抗霉素A复合物是一种细菌代谢产物,发现在链霉菌中,由主要成分抗霉素A1、-A2、-A3和-A4组成,以及包括抗霉素A5和-A6等少量成分。1 当浓度在3.3至160微摩尔范围内使用时,它能诱导海洋结核杆菌合成类胡萝卜素。2 抗霉素A复合物(25-125 ppb)对金鱼具有致死活性。1
References:
[1]. Kluepfel, D., Sehgal, S.N., and Vezina, C.Antimycin A components. I. Isolation and biological activity.J. Antibiot. (Tokyo)23(2)75-80(1970)
[2]. Batra, P.P., Harbin, T.L., Howes, C.D., et al.A study of the relationship of structure and activity of antimycin A in the induction of carotenoid synthesis in Mycobacterium marinumJ. Biol. Chem.246(23)7125-7130(1971)
















