IC50: 15 μM (RpMetAP1)[1]
Antibacterial agent 117, triazole derivative, is an antibacterial agent. Antibacterial agent 117 has against R. prowazekii MetAP1 (RpMetAP1) activity with an IC50 value of 15 μM. Antibacterial agent 117 also inhibits rickettsial growth and can be used for the research of infection[1].
Antibacterial agent 117 can inhibit RpMetAP1 with an IC50 value of 15 μM[1].
Antibacterial agent 117 (0.3 μM, 3 μM, 30 μM and 300 μM) stimulates endothelial cell (EC) metabolism and also inhibits rickettsial growth[1].
















