GlpBio

Anti-melanoma agent 1

目录号: GC73309纯度: >99.00%
Anti-melanoma agent 1（化合物5m）是一种抗黑色素瘤药物，可诱导细胞凋亡。
Anti-melanoma agent 1
Cas No.: 2418579-17-4
规格价格库存数量操作
5 mg¥765.00现货
1
10 mg¥1,170.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent and induces cell apoptosis.

Anti-melanoma agent 1 (Compound 5m) (0-100 μM, 48 h) shows antiproliferative activity against melanoma cells[1].Anti-melanoma agent 1 (0-10 μM) inhibits colony formation in SK-MEL-28[1].Anti-melanoma agent 1 (1 and 2 μM) induces cell apoptosis (24 h), arrests cell cycle at G2/M phase (12 h), inhibits cell migration (48 h) and disrupts the cellular microtubule network[1].

References:
[1]. Chang Q, et al. Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents. Bioorg Med Chem. 2020 May 1;28(9):115404.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
2418579-17-4
分子式
C28H28N2O2
分子量
424.53 g/mol
溶解性
DMSO : 100 mg/mL (235.55 mM; Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol