Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].
Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) 对角叉菜胶诱导的大鼠足水肿有抑制作用，对小鼠有缓解疼痛作用[1]。
| Animal Model: | Male albino rats, carrageenan-induced rat paw edema assay model[1] |
| Dosage: | 200 mg/kg |
| Administration: | Oral, single dose |
| Result: | Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h. |
| Animal Model: | Albino mice, acetic acid induced writhing method[1] |
| Dosage: | 200 mg/kg |
| Administration: | Oral, single dose |
| Result: | Showed 48.1% analgesic activity. |
[1]. Ronad PM, et al. Synthesis and evaluation of anti-inflammatory and analgesic activities of a novel series of substituted-N-(4-methyl-2-oxo-2H-chromen-7-yl) benzamides. Arzneimittelforschung. 2008;58(12):641-6.