GlpBio

AMPA receptor modulator-3

目录号: GC68438纯度: >98%
COASDSData Sheet
AMPA receptor modulator-3 是一种变构的 AMPA 受体调节剂 (EC50: 4.4 μM)。AMPA receptor modulator-3 可用于哺乳动物神经系统的研究，如学习和记忆能力。
AMPA receptor modulator-3
Cas No.: 211311-39-6
规格价格库存数量操作
1mg¥540.00现货
1
5mg¥1,350.00现货
1
25mg¥3,780.00现货
1
10mM (in 1mL DMSO)¥996.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM). AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2].

AMPA receptor modulator-3 (Compound 5e) shows an EC50 value of 4.4 μM for potentiation of responses mediated by 100 μM L-glutamate in HEK-293 cells expressing iGluR4 flip[2].

[1]. Kasper HarpsØe, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26(5):874-83. https://pubmed.ncbi.nl

产品文档 Product Documents

Purity:>98%
COASDSData Sheet

化学性质Chemical Properties

CAS 号
211311-39-6
分子式
C18H22FNO2S
分子量
335.44 g/mol
溶解性
DMSO : 250 mg/mL (745.29 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol