ADP-β-S trilithium is the trilithium salt form of ADP-β-S. ADP-β-S trilithium is the activator for P2Y12 receptor, which upregulates levels of IL-1βand IL-6 production in microglial cells, promotes the phosphorylation and nuclear translocation of NF-κB, and enhances the activation of the NLRP3 inflammasome[1].
Refence:
[1]. Suzuki T, et al., Extracellular ADP augments microglial inflammasome and NF-κB activation via the P2Y12 receptor. Eur J Immunol. 2020 Feb;50(2):205-219.