GlpBio

Adenylyl cyclase type 2 agonist-1

目录号: GC70966纯度: >99.00%
Adenylyl cyclase type 2 agonist-1（化合物73）是腺苷酸环化酶2型（AC2）的强效激动剂，EC50为90nM。
Adenylyl cyclase type 2 agonist-1
Cas No.: 2414908-52-2
规格价格库存数量操作
1 mg¥3,060.00现货
1
5 mg¥7,650.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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产品描述 Description

Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases.

References:
[1]. Guowei Xu, et al. The discovery, design and synthesis of potent agonists of adenylyl cyclase type 2 by virtual screening combining biological evaluation. Eur J Med Chem. 2020 Apr 1;191:112115.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

CAS 号
2414908-52-2
分子式
C27H17BrClNO5
分子量
550.78 g/mol
溶解性
DMSO : 25 mg/mL (45.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
保存条件
4°C, protect from light, stored under nitrogen
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol