GlpBio

AChE-IN-26

目录号: GC68609纯度: >99.00%
AChE-IN-26 (compound 4a) 是 AChE (acetylcholinesterase) 的抑制剂，IC50 值为 0.42 μM。AChE-IN-26 可用于阿尔兹海默症的研究。
AChE-IN-26
规格价格库存数量操作
5mg¥1,080.00现货
1
10mg¥1,710.00现货
1
25mg¥3,420.00现货
1
50mg¥5,580.00现货
1
100mg¥8,820.00现货
1
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

产品描述 Description

IC50: 0.42 μM (AChE)[1]

AChE-IN-26 (compound 4a) is an AChE (acetylcholinesterase) inhibitor with an IC50 value of 0.42 μM. AChE-IN-26 can be used for the research of Alzheimer's disease[1].

AChE-IN-26 (1 and 10 μM;20 min) shows an in-vitro inhibition to AChE of 91.45%, and inhibits AChE with an IC50 value of 0.42 μM[1].

[1]. Abdullaha M, et al. Discovery of methoxy-naphtl linked N-(1-benzylpiperidine) benzamide as a blood-brain permeable dual inhibitor of acetylcholinesterase and butyrylcholinesterase. Eur J Med Chem. 2020 Dec 1;207:112761.

产品文档 Product Documents

Purity:>99.00%

化学性质Chemical Properties

分子式
C21H21BrN2O3
分子量
429.31 g/mol
溶解性
DMSO : 250 mg/mL (582.33 mM; Need ultrasonic)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol