GlpBio

Acetylcorynoline

目录号: GN10240纯度: >98.00%同义词: 乙酰紫堇灵
Acetylcorynoline 是从延胡索中提取的主要生物碱成分，具有抗炎特性。
Acetylcorynoline
Cas No.: 18797-80-3
规格价格库存数量操作
20mg¥1,838.00现货
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文献被引

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1].

Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1].Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1].

References:
[1]. Fu RH, et al. Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease. Neuropharmacology. 2014 Jul;82:108-20.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
18797-80-3
同义词
乙酰紫堇灵
化学名
(5bR,6S,12bR)-5b,13-dimethyl-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-6-yl acetate
SMILES
O=C(C([H])([H])[H])O[C@](C([H])([H])C1=C2[H])([H])[C@@]3(C([H])([H])[H])[C@](C1=C([H])C4=C2OC([H])([H])O4)([H])N(C([H])([H])[H])C([H])([H])C5=C3C([H])=C([H])C6=C5OC([H])([H])O6
分子式
C23H23NO6
分子量
409.43 g/mol
溶解性
DMSO : 25 mg/mL (61.06 mM; Need ultrasonic)
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol