GlpBio

8-iso-15-keto Prostaglandin F2β

目录号: GC41427纯度: >95.00%同义词: 8<span class="\foreign\">epi</span>15keto PGF2α, 815keto PGF2α
A potential 8-iso prostaglandin F2β metabolite
8-iso-15-keto Prostaglandin F2&#946;
Cas No.: 1621482-36-7
规格价格库存数量操作
1mg¥5,597.00现货
1
100&#956;g¥878.00现货
1
500&#956;g¥3,203.00现货
1
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文献被引

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF2α. 8-iso-15-keto PGF2β is a potential metabolite of 8-iso PGF2β via the 15-hydroxy PG dehydrogenase pathway. There are no published reports on the formation or biological activity of 8-iso-15-keto PGF2β.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

CAS 号
1621482-36-7
同义词
8<span class="\foreign\">epi</span>15keto PGF2α, 815keto PGF2α
SMILES
O[C@@H]1C[C@@H](O)[C@@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/C(CCCCC)=O
分子式
C20H32O5
分子量
352.5 g/mol
溶解性
DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
保存条件
Store at -20&#176;C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol