GlpBio

(7R)-SBP-0636457

目录号: GC72962纯度: >98.00%同义词: (7R)-SBI-0636457; (7R)-SB1-0636457
(7R)-SBP-0636457是SBP-0636457的异构体，可以作为实验对照物。
(7R)-SBP-0636457
Cas No.: 1422180-61-7
规格价格库存数量操作
1 mg¥3,506.00现货
1
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文献被引

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产品描述 Description

(7R)-SBP-0636457 is the isomer of SBP-0636457 , and can be used as an experimental control. SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the IAP proteins, with a Ki of 0.27 μM. SBP-0636457 can be used for the research of solid tumors and hematologic cancers.

References:
[1]. Finlay D, et, al. Small-molecule IAP antagonists sensitize cancer cells to TRAIL-induced apoptosis: roles of XIAP and cIAPs. Mol Cancer Ther. 2014 Jan; 13(1): 5-15.
[2]. Finlay D, et, al. Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins. F1000Res. 2017 Apr 27; 6:587.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
1422180-61-7
同义词
(7R)-SBI-0636457; (7R)-SB1-0636457
分子式
C25H36N4O4
分子量
456.58 g/mol
溶解性
DMSO : 5 mg/mL (10.95 mM; ultrasonic and warming and heat to 60°C)
保存条件
4°C, stored under nitrogen
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol