7-Methylcoumarin can inhibit the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8–3.6 μg/ml, and also has a strong hepatoprotective activity.
7-methylcoumarin is equipotent in inhibiting the growth of S. aureus and the growth of Gram-positive bacteria within a concentration of 0.8-3.6 μg/ml, displaying no effects against Gram-negative bacteria and fungi.[1]
Pretreatment with MC significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST) and serum bilirubin (TB) in the serum of CCl(4)-induced liver damaged rats in a dose-dependent manner, also prevents oxidative stress induced by CCl(4), thereby, increasing superoxide dismutase (SOD) and catalase (CAT) levels and decreasing thiobarbituric-acid-related substances (TBARS) levels in liver homogenates.[2]
[1] El-Gendy MM, et al. Appl Biochem Biotechnol. 2008 Jul;150(1):85-96. [2] Sancheti S, et al. Drug Chem Toxicol. 2013 Jan;36(1):42-7.