7-Ketositosterol is a phytosterol and phytosterol oxidation product (POP).1,2 It is a thermal oxidation product of sitosterol .2 7-Ketositosterol inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells (IC50 = 45.6 µM).3
1.Yu, J.-D., Chen, M.-X., Wu, H., et al.Phytochemical and chemotaxonomic study on Pholidota pallida lindlBiochem. Syst. Ecol.97104290(2021) 2.McDonald, K., Langenbahn, H.J., Miller, J.D., et al.Phytosterol oxidation products from coffee silverskinJ. Food Sci.87(2)728-737(2022) 3.Oyama, M., Tokiwano, T., Ota, H., et al.β-sitosterol oxides from the dried stem of salix gilgiana inhibit the proliferation of HL-60 leukemic cellsCurr. Bioact. Compd.16(3)329-334(2020)
















