7-Hydroxy-4-methyl-8-nitrocoumarin is a coumarin derivative with antibacterial and antioxidant activities.1,2 It is active against S. aureus and E. coli in a disc assay when used at concentrations of 50 and 100 µg/disc.1 7-Hydroxy-4-methyl-8-nitrocoumarin inhibits NADPH-dependent lipid peroxidation in rat liver microsomes.2
1.Sahoo, S.S., Shukla, S., Nandy, S., et al.Synthesis of novel coumarin derivatives and its biological evaluationsEur. J. Exp. Biol.2(4)899-908(2012) 2.Tyagi, Y.K., Kuma, A., Raj, H.G., et al.Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activityEur. J. Med. Chem.40(4)413-420(2005)