GlpBio

7α-Thiospironolactone

目录号: GC49391纯度: >90.00%同义词: Deacetylspironolactone, Mercaptospironolactone, SC-24813, 7α-Thio-SL
An active metabolite of spironolactone
7α-Thiospironolactone
Cas No.: 38753-76-3
规格价格库存数量操作
1 mg¥1,309.00现货
1
5 mg¥4,410.00现货
1
10 mg¥8,085.00现货
1
500 µg¥693.00现货
1
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产品描述 Description

7α-Thiospironolactone (7α-Thio-SL) is an active metabolite of the synthetic steroid spironolactone.1 In vivo, 7α-thio-SL (100 mg/kg) decreases plasma testosterone and estradiol levels in male dogs.2 It reduces mercuric chloride-induced nephrocalcinosis and mortality in rats.3

1.Los, L.E., Coddington, A.B., Ramjit, H.G., et al.Identification of spironolactone metabolites in plasma and target organs of guinea pigsDrug Metab. Dispos.21(6)1086-1090(1993) 2.Menard, R.H., Loriaux, D.L., Bartter, F.C., et al.The effect of the administration of spironolactone on the concentration of plasma testosterone, estradiol and cortisol in male dogsSteroids31(6)771-782(1978) 3.Szabo, S., and Gagnon, M.J.The protective effect of sulfur-containing steroids against nephrocalcinosis induced by mercuric chloride in ratsGen. Pharmacol.14(2)269-272(1983)

产品文档 Product Documents

Purity:>90.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
38753-76-3
同义词
Deacetylspironolactone, Mercaptospironolactone, SC-24813, 7α-Thio-SL
SMILES
C[C@@]12[C@@]3(OC(CC3)=O)CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H]4S)=CC(CC5)=O)C)([H])CC2
分子式
C22H30O3S
分子量
374.5 g/mol
溶解性
Ethanol: soluble
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol