7,10-dihydroxy-8(E)-Octadecenoic acid is a hydroxy fatty acid and metabolite of oleic acid that is produced by P. aeruginosa from vegetable oils.1 It is active against the food-borne pathogenic bacteria S. aureus, S. typhimurium, L. monocytogenes, B. subtilis, and E. coli (MIC50s = 31.3, 125, 125, 62.5, and 250 µg/ml, respectively), as well as the plant pathogenic bacteria Erwinia, R. solanacearum, C. glutamicum, and P. syringae (MIC90s = 125, 125, 250, and 500 µg/ml, respectively).2,1
1.Sohn, H.-R., Bae, J.-H., Hou, C.T., et al.Antibacterial activity of a 7,10-dihydroxy-8(E)-octadecenoic acid against plant pathogenic bacteriaEnzyme Microb. Technol.53(3)152-153(2013) 2.Chen, K.Y., Kim, I.H., Hou, C.T., et al.Monoacylglycerol of 7,10-dihydroxy-8(E)-octadecenoic acid enhances antibacterial activities against food-borne bacteriaJ. Agric. Food Chem.67(29)8191-8196(2019)