GlpBio

6-Aminochrysene (6-Chrysenamine)

目录号: GC31932纯度: >98.00%同义词: 7-胺基去乙酰氧基头胞烷酸,6-Chrysenamine
A carcinogen and anticancer agent
6-Aminochrysene (6-Chrysenamine)
Cas No.: 2642-98-0
规格价格库存数量操作
25mg¥468.00现货
1
10mM (in 1mL DMSO)¥515.00现货
1
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文献被引

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产品描述 Description

6-Chrysenamine is a carcinogen and an anticancer agent.1,2 Neonatal administration of 6-chrysenamine (600 ?g/animal; s.c.) induces the formation of hepatomas and pulmonary adenocarcinomas in adult mice.1 6-Chrysenamine (3-110 mg/kg) inhibits tumor growth in an EO771 murine mammary carcinoma model.2

1.Roe, F.J., Carter, R.L., and Adamthwaite, S.Induction of liver and lung tumours in mice by 6-aminochrysene administered during the 1st 3 days of lifeNature221(5185)1063-1064(1969) 2.Gelzer, J., and Loustalot, P.Chrysenex? in experimental advanced mammary cancerEur. J. Cancer3(1)79-80(1967)

实验参考方法 Experimental Reference Method

Animal experiment:

Rats: Male CD rats are pre-treated with 25, 50 and 100 mg/kg of 6-Aminochrysene intraperitoneally once daily for 3 consecutive days before sacrifice, which is performed 24 h after the last administration. Controls receive only the solvent[1].

References:

[1]. Russo R, et al. Effects of 6-aminochrysene on liver microsomal enzyme activity. Xenobiotica. 1976 Apr;6(4):201-5.
[2]. Lambelin G, et al. Carcinogenicity of 6-aminochrysene in mice. Eur J Cancer. 1975 May;11(5):327-34.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
2642-98-0
同义词
7-胺基去乙酰氧基头胞烷酸,6-Chrysenamine
SMILES
NC1=C2C=CC=CC2=C3C(C4=CC=CC=C4C=C3)=C1
分子式
C18H13N
分子量
243.3 g/mol
溶解性
DMSO : ≥ 62.5 mg/mL (256.88 mM)
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol