GlpBio

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

目录号: GC49339纯度: >90.00%同义词: 5[6]-羧基-2',7'-二氯荧光素二乙酸酯
An oxidant-sensitive fluorescent probe
5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate
Cas No.: 127770-45-0
规格价格库存数量操作
25 mg¥798.00现货
1
50 mg¥1,246.00现货
1
100 mg¥1,696.00现货
1
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文献被引

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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    31, 1291–1307 (2021)

产品描述 Description

5(6)-Carboxy-2’,7’-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1 Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5(6)-carboxy-2’,7’,-dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.

1.Hempel, S.L., Buettner, G.R., O’Malley, Y.Q., et al.Dihydrofluorescein diacetate is superior for detecting intracellular oxidants: Comparison with 2’,7’-dichlorodihydrofluorescein diacetate, 5(and 6)-carboxy-2’,7’-dichlorodihydrofluorescein diacetate, and dihydrorhodamine 123Free Radic. Biol. Med.27(1-2)146-159(1999)

产品文档 Product Documents

Purity:>90.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
127770-45-0
同义词
5[6]-羧基-2',7'-二氯荧光素二乙酸酯
SMILES
O=C(O1)C2=C(C=CC(C(O)=O)=C2)C31C4=CC(Cl)=C(OC(C)=O)C=C4OC5=C3C=C(Cl)C(OC(C)=O)=C5.O=C(O6)C7=C(C=C(C(O)=O)C=C7)C86C9=CC(Cl)=C(OC(C)=O)C=C9OC%10=C8C=C(Cl)C(OC(C)=O)=C%10
分子式
C25H14Cl2O9
分子量
529.3 g/mol
溶解性
DMF: 30 mg/ml,DMSO: 30 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol