4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].
4-Cumylphenol (1, 5, 10, 20, 40 µM; 6 days) increase lipid accumulation in 3 T3-L1 cells[3].
Cell Viability Assay[3]
| Cell Line: | 3 T3-L1 cells |
| Concentration: | 1, 5, 10, 20, 40 µM |
| Incubation Time: | 6 days |
| Result: | Increase lipid accumulation, which peaked at10 μM with a 204% increase. |
[1]. Yue W, et al. Biodegradation of bisphenol-A polycarbonate plastic by Pseudoxanthomonas sp. strain NyZ600. J Hazard Mater. 2021 Aug 15;416:125775.
[2]. Chiha M, et al. Sonolytic degradation of endocrine disrupting chemical 4-cumylphenol in water. Ultrason Sonochem. 2011 Sep;18(5):943-50.
[3]. Ramskov Tetzlaff CN, Svingen T, et al. Bisphenols B, E, F, and S and 4-cumylphenol induce lipid accumulation in mouse adipocytes similarly to bisphenol A. Environ Toxicol. 2020 May;35(5):543-552.