4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent[1].
4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys[1].
| Animal Model: | Diet-induced hypercholesterolemic African green monkeys[5] |
| Dosage: | 15-60 mg/kg |
| Administration: | Oral administration (p.o.) |
| Result: | Reduced serum LDL-cholesterol concentrations. |
[1]. Lewis MC, et al. Evaluation of the hypolipidemic activity of xenalipin in experimental animals. Atherosclerosis. 1987 Mar;64(1):27-35.