GlpBio

3’-Azido-2’,3’-dideoxyuridine

目录号: GC49871纯度: >95.00%同义词: 3'-叠氮-2',3'-双脱氧尿苷
An antiviral nucleoside analog
3’-Azido-2’,3’-dideoxyuridine
Cas No.: 84472-85-5
规格价格库存数量操作
5 mg¥788.00现货
1
10 mg¥1,344.00现货
1
25 mg¥2,781.00现货
1
50 mg¥4,496.00现货
1
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产品描述 Description

3’-Azido-2’,3’-dideoxyuridine (AZddU) is an antiviral nucleoside analog.1 It is phosphorylated by thymidine kinase.2 AZddU inhibits cytopathogenicity induced by HIV or Moloney sarcoma virus (MSV) in MT-4 cells (EC50s = 0.36 and 15 µM, respectively).1

1.Balzarini, J., Baba, M., Pauwels, R., et al.Anti-retrovirus activity of 3’-fluoro- and 3’-azido-substituted pyrimidine 2’,3’-dideoxynucleoside analoguesBiochem. Pharmacol.37(14)2847-2856(1988) 2.Eriksson, B.F., Chu, C.K., and Schinazi, R.F.Phosphorylation of 3’-azido-2’,3’-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5’-triphosphateAntimicrob. Agents Chemother.33(10)1729-1734(1989)

产品文档 Product Documents

Purity:>95.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
84472-85-5
同义词
3'-叠氮-2',3'-双脱氧尿苷
SMILES
O=C1N([C@@]2([H])C[C@@H]([C@H](O2)CO)N=[N+]=[N-])C=CC(N1)=O
分子式
C9H11N5O4
分子量
253.2 g/mol
溶解性
DMF: 2 mg/ml,DMSO: 2 mg/ml,Ethanol: insol,PBS (pH 7.2): 1 mg/ml
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol