3-Methylsalicylic acid is a derivative of salicylic acid. It has been used in the synthesis of salicylamides with in vitro anticancer activity.1 3-Methylsalicylic acid has also been used in the synthesis of pyrimethamine-salicylic acid salts.2
1.Chae, H.-D., Cox, N., Capolicchio, S., et al.SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathwayBioorg. Med. Chem. Lett.29(16)2307-2315(2019) 2.Ceborska, M., K?dra-Królik, K., Narodowiec, J., et al.Influence of hydroxyl group position and substitution pattern of hydroxybenzoic acid on the formation of molecular salts with the antifolate pyrimethamineCryst. Growth Des.21(12)6714-6726(2021)