3'-Azido-ddATP是一种单体原料，可用于核酸合成。
Sample solution is provided at 25 µL, 10mM.
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3'-Azido-ddATP is a monomeric raw material that can be applied for nucleic acid synthesis [1]. 3'-Azido-ddATP can be widely used as a substrate to detect the enzymatic activity of recombinant HIV-1 reverse transcriptase[2].
References:
[1] Herman B D, Schinazi R F, Zhang H, et al. Substrate mimicry: HIV-1 reverse transcriptase recognizes 6-modified-3′-azido-2′, 3′-dideoxyguanosine-5′-triphosphates as adenosine analogs[J]. Nucleic acids research, 2012, 40(1): 381-390.
[2] Sluis-Cremer N, Koontz D, Bassit L, et al. Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3′-azido-2′, 3′-dideoxypurine nucleosides[J]. Antimicrobial agents and chemotherapy, 2009, 53(9): 3715-3719.
3'-Azido-ddATP是一种单体原料，可用于核酸合成[1]。3′-Azido-ddATP可广泛用作检测重组HIV-1逆转录酶酶活性的底物[2]。
| Cas No. | SDF | Download SDF | |
| 分子式 | C10H15N8O11P3(free acid) | 分子量 | 516.2 (free acid) |
| 溶解度 | 储存条件 | -20°C or below, always avoid freeze-thaw cycles. | |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.9372 mL | 9.6862 mL | 19.3723 mL |
| 5 mM | 387.4 μL | 1.9372 mL | 3.8745 mL |
| 10 mM | 193.7 μL | 968.6 μL | 1.9372 mL |
Quality Control & SDS
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- Purity: >98.50% Appearance: A solution
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet