2-Chloro-N-methyl-N-(4-nitrophenyl)acetamide is a synthetic intermediate.1 It has been used in the synthesis of maternal embryonic leucine zipper kinase (MELK) inhibitors with anticancer activity.
1.Edupuganti, R., Taliaferro, J.M., Wang, Q., et al.Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growthBioorg. Med. Chem.25(9)2609-2616(2017)
















