GlpBio

2,4-Diamino-6-hydroxypyrimidine

目录号: GC16996纯度: >98.00%同义词: 2,4-二氨基-6-羟基嘧啶
A selective, specific inhibitor of GTP cyclohydrolase I
2,4-Diamino-6-hydroxypyrimidine
Cas No.: 56-06-4
规格价格库存数量操作
50mg¥809.00现货
1
10mM (in 1mL DMSO)¥378.00现货
1
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产品描述 Description

2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production[1].

References:
[1]. Sung YJ, et al. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol. 1994 Feb;16(2):101-8.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
56-06-4
同义词
2,4-二氨基-6-羟基嘧啶
化学名
2,6-diaminopyrimidin-4(1H)-one
SMILES
O=C1N=C(N)NC(N)=C1
分子式
C4H6N4O
分子量
126.12 g/mol
溶解性
DMF: >14.4 mg/ml,DMSO: >14.6 mg/ml,Ethanol: <50 µ g/ml,PBS pH 7.2: >3.3 mg/ml
保存条件
4°C, protect from light
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol