GlpBio

2,3,4,7,8-Pentachlorodibenzofuran

目录号: GC90944纯度: >85.00%同义词: 2,3,4,7,8-PCDF, PCDF, PCDF 114

一种类似二恶英的多氯联苯。

2,3,4,7,8-Pentachlorodibenzofuran
Cas No.: 57117-31-4
规格价格库存数量操作
5 mg¥4,270.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

2,3,4,7,8-Pentachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF).1 It induces the expression of genes encoding the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2 in primary human hepatocytes (EC50s = 0.369 and 0.329 nM, respectively) and aryl drocarbon droxylase (AHH) and ethoxyresorufin-O-deetlase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 0.256 and 0.134 nM, respectively).2,3 Serum levels of 2,3,4,7,8-pentachlorodibenzofuran are elevated in humans that consumed products from plants and animals grown and raised in dioxin-contaminated river sediments.1 2,3,4,7,8-Pentachlorodibenzofuran (300 µg/kg) decreases maternal and fetal weight and the number of live fetuses, as well as increases maternal tmus and liver weight and the percentage of fetuses with cleft palate, in developing fetuses in pregnant rat dams.4

产品文档 Product Documents

Purity:>85.00%Appearance:A solid

化学性质Chemical Properties

CAS 号
57117-31-4
同义词
2,3,4,7,8-PCDF, PCDF, PCDF 114
分子式
C12H3Cl5O
分子量
340.4 g/mol
溶解性
Acetone: Slightly soluble w/ sonication,Benzene: Slightly soluble
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol