GlpBio

(±)17-HDHA

目录号: GC41197纯度: >98.00%同义词: 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-HDoHE
An autoxidation product of DHA and potential marker of oxidative stress
(±)17-HDHA
Cas No.: 90780-52-2
规格价格库存数量操作
50μg¥1,848.00现货
1
100μg¥3,480.00现货
1
250μg¥8,177.00现货
1
25μg¥1,032.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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产品描述 Description

(±)17-HDHA is an autoxidation product of docosahexaenoic acid in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of mammalian 15-LOs. 17(S)-HDHA was shown to be an inhibitor of U-46619 -induced rabbit and rat aortic smooth muscle contraction with IC50 values of 4.9 and 7.2 µM, respectively. (±)17-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

产品文档 Product Documents

Purity:>98.00%

化学性质Chemical Properties

CAS 号
90780-52-2
同义词
17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-HDoHE
SMILES
CC/C=C\CC(O)\C=C\C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O
分子式
C22H32O3
分子量
344.5 g/mol
溶解性
0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS (pH 7.2): 0.8 mg/ml
保存条件
Store at -20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol