GlpBio

(16R)-Epothilone D

目录号: GC73402纯度: >95.00%同义词: (16R)-埃博霉素; (16R)-KOS 862
(16R)-Epothilone D是埃博霉素D的异构体并且可以用作实验对照。
(16R)-Epothilone D
规格价格库存数量操作
2 mg¥585.00现货
1
5 mg¥1,125.00现货
1
10 mg¥1,800.00现货
1
25 mg¥3,600.00现货
1
50 mg¥5,400.00现货
1
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文献被引

本产品暂无引用记录;以下为 GlpBio 产品在 Nature / Cell / Science 等顶刊的客户引用样例
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

产品描述 Description

(16R)-Epothilone D is the isomer of Epothilone D , and can be used as an experimental control. Epothilone D (KOS 862) is a potent microtubule stabilizer.

References:
[1]. Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopat. J Neurosci. 2010 Oct 13;30(41):13861-6.
[2]. Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

同义词
(16R)-埃博霉素; (16R)-KOS 862
分子式
C27H41NO5S
分子量
491.68 g/mol
溶解性
Methanol : 69.25 mg/mL (140.84 mM; Need ultrasonic)
保存条件
-20°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol