13C6-4-Nitrophenylhydrazine (hydrochloride)

¹³C₆-4-Nitrophenylhydrazine is intended for use as an internal standard for the quantification of 4-nitrophenylhydrazine by GC- or LC-MS. ¹³C₆-4-Nitrophenylhydrazine is a byproduct in the synthesis of ¹³C₆-3-nitrophenylhydrazine . 4-Nitrophenylhydrazine has been used as an intermediate in the synthesis of benzo-indazole derivatives with anti-uterotrophic activity in vivo and pyrazolobenzothiazine derivatives with antiviral activity in vitro.^[1],[2]

References:
[1].Ragab, M.A., Elagawany, M., Daabees, H., et al.Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activityBioorg. Chem.119105554(2022).
[2].Barreca, M.L., Manfroni, G., Leyssen, P., et al.Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replicationJ. Med. Chem.56(6)2270-2282(2013).