(-)-11-hydroxy-δ8-THC-d3 (exempt preparation)

(−)-11-hydroxy-Δ⁸-THC-d₃ (exempt preparation) is intended for use as an internal standard for the quantification of (−)-11-hydroxy-Δ⁸-THC by GC- or LC-MS. (−)-11-hydroxy-Δ⁸-THC is categorized as a phytocannabinoid metabolite.^[1],[2] (–)-11-hydroxy-Δ⁸-THC is a metabolite of Δ⁸-THC . It has analgesic activity in mice. (–)-11-hydroxy-Δ⁸-THC-d₃ is regulated as a Schedule I compound in the United States. (−)-11-hydroxy-Δ⁸-THC-d₃ (exempt preparation) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

References:
[1].Watanabe, K., Yamamoto, I., Oguri, K., et al.Comparison in mice of pharmacological effects of Δ8-tetrahydrocannabinol and its metabolites oxidized at 11-positionEur. J. Pharm.63(1)1-6(1980).
[2].Rhee, M.H., Vogel, Z., Barg, J., et al.Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclaseJ. Med. Chem.40(20)3228-3233(1997).