1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated form of lysophosphatidylcholine (Lyso-PC) [1]. 1‑Stearoyl‑2‑hydroxy‑sn‑glycero‑3‑PC is a major component of oxidized low-density lipoprotein and is believed to have an important role in inflammatory diseases and atherosclerosis [2-3].
References:
[1]. Milne G L, Seal J R, Havrilla C M, et al. Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins[J]. Journal of lipid research, 2005, 46(2): 307-319.
[2]. Leitinger N. A role for phospholipid oxidation products as modulators of inflammatory reactions in atherogenesis[J]. Acta Angiologica, 2002, 8(4): 117-126.
[3]. Shrestha R, Chiba H, Hui S P. Oxidized lipid species in lipoproteins: Significance and analytical considerations[J]. Medical Mass Spectrometry, 2020, 4(1): 2-23.
1-Stearoyl-2-hydroxy-sn-glycero-3-PC是一种饱和形式的溶物磷脂酰胆碱（Lyso-PC） [1]。1‑Stearoyl‑2‑hydroxy‑sn‑glycero‑3‑PC是氧化低密度脂蛋白的主要成分，被认为在炎症性疾病和动脉粥样硬化中发挥重要作用 [2-3]。