GLPBio

1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)

目录号: GC92174纯度: >95.00%同义词: 1-Arachidonoyl LPA; 1-Arachidonoyl Lysophosphatidic Acid; 1-Eicosatetraenoyl-2-hydroxy-sn-glycero-3-phosphate; 20:4 LPA; LPA 20:4; PA(20:4/0:0)
1-Arachidonoyl-2-droxy-sn-glycero-3-PA is a phospholipid containing arachidonic acid at the sn-1 position.
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA (sodium salt)
规格价格库存数量操作
500ug¥739.00现货
1
1mg¥1,401.00现货
1
5mg¥5,914.00现货
1
10mg¥11,088.00现货
1
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文献被引

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6734) (2025)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

产品描述 Description

1-Arachidonoyl-2-droxy-sn-glycero-3-PA is a phospholipid containing arachidonic acid at the sn-1 position. It has been found in rat brain as 37% of the arachidonic acid-containing lysophosphatidic acid (LPA) species and is a precursor to 1-arachidonoyl glycerol . 1-Arachidonoyl-2-droxy-sn-glycero-3-PA binds to the LPA2/EDG4 receptor with an EC50 value of approximately 10 nM. It prevents TNF-α and IL-6 secretion in wild-type but not Lpa2-/- dendritic cells stimulated by LPS. It also decreases differentiation of HT-29 human colon carcinoma cells to goblet cells in the presence of sodium butyrate.

产品文档 Product Documents

Purity:>95.00%

化学性质Chemical Properties

同义词
1-Arachidonoyl LPA; 1-Arachidonoyl Lysophosphatidic Acid; 1-Eicosatetraenoyl-2-hydroxy-sn-glycero-3-phosphate; 20:4 LPA; LPA 20:4; PA(20:4/0:0)
化学名
(5Z,8Z,11Z,14Z)-eicosatetraenoic acid, (2R)-hydroxy-3-(phosphonooxy)propyl ester, monosodium salt
SMILES
O[C@@H](COP([O-])(O)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O.[Na+]
分子式
C23H38O7P • Na
分子量
480.513531 g/mol
溶解性
Methanol: Sparingly soluble
保存条件
-80°C
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
为了提高溶解度，请将管子加热至 37°C，然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备 RT，或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol