1'-epi Gemcitabine hydrochloride

目录号: GC74183纯度: >98.00%同义词: 1'-epi LY 188011 hydrochloride
1'-epi Gemcitabine hydrochloride是盐酸吉西他滨的异构体,可用作实验对照。

1'-epi Gemcitabine hydrochloride
Cas No.: 122111-05-1
规格价格库存数量操作
1 mg¥2,079.00现货
1

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产品描述 Description

1'-epi Gemcitabine drochloride is the isomer of Gemcitabine drochloride , and can be used as an experimental control. Gemcitabine drochloride (LY 188011 drochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine drochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis.

References:
[1]. Yip-Schneider MT, et al. Dimetlaminoparthenolide and Gemcitabine: a survival study using a genetically engineered mouse model of pancreatic cancer. BMC Cancer. 2013 Apr 17;13:194.
[2]. Lou M, et al. Psical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. J Biol Chem. 2017 Jun 2;292(22):9136-9149.
[3]. Gagnadoux F, et al. Safety of pulmonary administration of gemcitabine in rats. J Aerosol Med. 2005 Summer;18(2):198-206
[4]. Wang H, et al. Enhanced efficacy of Gemcitabine by indole-3-carbinol in pancreatic cell lines: the role of human equilibrativenucleoside transporter 1. Anticancer Res. 2011 Oct;31(10):3171-80

产品文档 Product Documents

Purity:>98.00%Appearance:A liquid

化学性质Chemical Properties

CAS 号
122111-05-1
同义词
1'-epi LY 188011 hydrochloride
分子式
C9H12ClF2N3O4
分子量
299.66 g/mol
保存条件
-20°C, sealed storage, away from moisture
General tips
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至 37°C,然后在超声波浴中震荡一段时间。
Shipping Condition
评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备 RT,或根据请求配备蓝冰。

计算工具摩尔浓度 / 稀释 / 分子量 / 单位换算 / 体内配方 / 溶解度

g/mol